Friends Not Included

Other online games offered by the people who make Ticket To Ride include:

Gang Of Four Online: A purportedly Chinese game where players try to get rid of their cards by forming better poker-style hands than the last player. The highest ranking hand is called "A Gang Of Four," but the rules forget to state which of those cards represents ex-propaganda minister Yao Wenyuan. I'm betting it's the Green-10.
Availability: There always seems to be 3-10 games of this going on at any particular time.

The Queen's Jewels: You play a jeweler, trying to sell gems to random people on the street. The gameplay described reminds me of a mashup between Renfeild and Bleeding Sherwood. I don't know for sure, because I have yet to play The Queen's Jewels. I also have yet to play Renfield or Bleeding Sherwood, even though Cheapass Games gives both of those away for free.
Availability: 1-3 people sullenly hanging out in the waiting room.

Fist of DragonstOnes: According to Days Of Wonder: "You will like it if you liked... Dungeons & Dragons™, the Lord of the Rings™ or Harry Potter™"
Availability: Give it a try. You'll be the first!

One product of theirs that you can't try out online is Shadows Over Camelot. The basic gameplay revolves around heroic knights working together to accomplish quests by assembling specific cards. Meanwhile, every round something terrible happens to undermine said players. The fun part is that in the beginning of the game, each of the players secretly gets one of 8 cards. Seven of them tell the player that they are loyal knights of Camelot. One of them lets that player know that they are a traitor, who will only win if the other players lose.

If too many black swords are gained for the forces of evil, the knights are overrun and killed by the forces of evil. "Accidentally" failing a quest gets the team black swords. Failing to catch the traitor gains the team black swords. Accusing someone of being a traitor gains the team black swords. Reminding the team that there is a mathematical chance that there is no traitor playing does not gain the team black swords, but seems awfully suspicious. Other suspicious activities include not doing quests to draw more cards, completing the best quests to steal their rewards, and completing the boring quests so that they do the least possible damage to the forces of evil.

The rampant suspicion that flows through this game is one main reason that this will never be offered online: The required paranoia necessary to play Shadows Over Camelot simply cannot be achieved through instant messages. Also, the game prohibits table talk, and you're going to have a hard enough time stopping that when you're all in the same room, let alone a virtual space where people could cheat like crazy through AIM.

Like a lot of games for three or more players, you do not want to bother with only three players. Also, the game is about this is exactly the kind of game Cheapass Games is talking smack about in their company philosophy. Fifty bucks gets you a clever design idea, and a plethora of soft rubber pawns that stride atop a full color abstract gameboard. It's nice, but I'd rather pay twelve bucks for it and have a tiny scavenger hunt in my apartment instead.
"Okay guys, we still need four pawns representing invading Saxons, a pawn representing the holy grail, and something to track the inevitable corruption of a utopian dream."